Sietse-Jan Weijenberg studied with Jan Ype Nota at the Groningen Conservatory, the Netherlands, and Michel Strauss at the CNSM of Paris, while taking masterclasses with Richard Aaron, Janos Starker, Natalia Gutman and others.

Sietse-Jan is a laureate of many competitions, most recently taking a top prize at the 2009 Rostropovich Competition. Since 2010 Sietse-Jan performs as principal cellist at various Dutch orchestras, such as the Residentieorkest, the Noord Nederlands Orkest, the Nederlands Kamerorkest and the Concertgebouw Orchestra. Also successful as a chambermusician, his trio won first prize at the Maria Canals Piano Trio competition 2009. He is a regular guest of international festivals like the Peter the Great Festival, the festival Musique à Giverny, the Storioni Festival or the Kuhmo Festival.

He appears frequently as a soloist, having performed a substantial part of the concertante repertory with orchestras such as Amsterdam Sinfoniëtta, the National Dutch Student Orchestra or the Orchestre de Paris. Sietse-Jan plays a cello by Antonio Pelizon (Gorizia, 1839), on loan from the collection of the Dutch Musical Instruments foundation.